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Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

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Genetic tumour heterogeneity, driven by clonal evolution, contributes to therapy resistance in many cancers. Most salivary gland cancers, including adenoid cystic carcinoma (AdCC) and myoepithelial carcinoma (MECA), lack effective systemic treatments, highligh... ...