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Normal Tissue Dosimetry of Intraperitoneal 224Ra Microparticle Therapy: Data from First-in-Human Studies in Patients with Peritoneal Metastases

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Two early-phase clinical studies evaluated α-emitting 224Ra adsorbed to calcium carbonate microparticles ([224Ra]CaCO3-MP). Patients with peritoneal metastases from ovarian or colorectal cancer underwent complete cytoreductive surgery 2 days before intraperit... ...