Mi3 nanoparticles displaying the knob domains of Fiber1 and Fiber2 from fowl adenovirus serotype 4 induce robust humoral and cellular immune responses in chickens
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Hepatitis-hydropericardium syndrome (HHS) caused by fowl adenovirus serotype 4 (FAdV-4) has led to substantial economic losses in the poultry industry. Subunit vaccines based on the knob domains of Fiber1 and Fiber2 (F1F2K) are safe but exhibit limited immunog... ...
