Design, synthesis and antitubercular evaluation of 2,5-disubstituted 1,3,4-oxadiazoles bearing a 3,5-dinitrophenyl pharmacophore
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Tuberculosis (TB) continues to demand new chemotypes able to overcome acquired drug-resistance. Here, we designed and synthesized two related series of twenty 3,5-dinitrophenyl-based 1,2-diacylhydrazines and their cyclic analogues, 2,5-disubstituted 1,3,4-oxad... ...
