Structural insights into UMP recognition and ligand specificity of orotidine 5'-Monophosphate decarboxylase from Fusobacterium nucleatum
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Orotidine-5'-phosphate decarboxylase (OMP decarboxylase; ODCase) catalyzes a key step in de novo pyrimidine biosynthesis by converting orotidine-5'-monophosphate to uridine-5'-monophosphate. Despite its essential metabolic role, the structural basis underly... ...
