AKAP12 is upregulated by base deletion at positions 61-78 in exon 3, leading to suppressed proliferation and metastasis of benzo[a]pyrene-transformed HBE cells
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The carcinogenic mechanism of benzo[a]pyrene (BaP) is not fully understood. Our previous studies unexpectedly revealed that A-kinase anchoring protein 12 (AKAP12), a recognized tumor suppressor frequently downregulated in malignancies, is markedly upregulated ... ...
