STING deficiency does not rescue short telomere-mediated aging phenotypes and longevity in TERC- or TERT-telomerase deficient mice
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The cyclic GMP-AMP synthase (cGAS)-stimulator of interferon genes (STING) pathway plays a key role in responding to viral genomes and endogenous DNA byproducts by inducing inflammatory pathways. Its roles in senescence and in the response to telomere shortenin... ...
