High-altitude hypoxia remodels lipid metabolism in renal tubular epithelial cells by inhibiting the expression of HNF4α
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A deficiency of fatty acid oxidation (FAO) is the key hallmark in renal tubular epithelial cells (TECs) under high-altitude hypoxia (HH), reflecting their physiological reliance on FAO as a major energy source. The resulting lipid accumulation is likely to pro... ...
