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Quantitative comparison of PI(3,5)P2 biosensors reveals SnxA is the most sensitive and unbiased

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PI(3,5)P2 is an endosomal lipid whose depletion is associated with a variety of pathologies such as neurodegenerative diseases. However, studying this lipid in physiological and disease models has been difficult due to the scarcity of the lipid and the lack of... ...