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The C5a-C5aR1 axis facilitates blood-brain barrier disruption induced by EV-A71 infection through neutrophil activation

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Enterovirus A71 (EV-A71), a member of the genus Enterovirus within the family Picornaviridae, induces neuroinflammation; however, the underlying mechanisms remain incompletely understood. This study demonstrates that the C5a-C5aR1 axis plays a pivotal role in ... ...