Transcriptome analysis reveals IGF-dependent and IGF-independent mechanisms affected by loss of IGF binding protein-2b in rainbow trout
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In teleosts, insulin-like growth factor binding protein-2b (IGFBP-2b) is the major carrier of serum insulin-like growth factor (IGF). A line of gene edited rainbow trout (2bKO) was produced that lack a functional IGFBP-2b and associated phenotypes of reduced s... ...
