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Shared parts, different structures: How asymmetry drives IgM and IgA structure-function relationships

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Polymeric (p) immunoglobulins (Igs) and their secretory (S) forms are critical to vertebrate immunity. The pIgs and SIgs comprise a molecularly diverse family of antibodies that contain multiple Ig monomers, up to one joining chain (JC), and up to one secretor... ...