Pegtarazimod limits acute graft-versus-host disease mortality and severity in mice and is tolerated in patients
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The success of allogeneic hematopoietic cell transplantation (allo-HCT) is limited by acute graft-versus-host disease (aGVHD). We have previously reported that neutrophils can exacerbate tissue damage caused by conditioning regimens. Pegtarazimod is a syntheti... ...
