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Development of Protium heptaphyllum essential oil-loaded nanocapsules: experimental design and biological activity

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Poly(ε-caprolactone) nanocapsules containing breu branco (Protium heptaphyllum) essential oil were successfully prepared by nanoprecipitation and optimized using a Box-Behnken design. Spherical nanosystems were obtained, with a mean particle size of 172.10 ±... ...