首页 正文

O-GlcNAc transferase as an oncogenic regulator in hematologic malignancies: Mechanisms, disease contexts, and therapeutic perspectives

{{output}}
O-GlcNAc transferase (OGT) catalyzes the addition of N-acetylglucosamine to serine and threonine residues of nuclear and cytoplasmic proteins, coupling cellular metabolic state to the post-translational regulation of hundreds of substrates. Hematologic maligna... ...