Topical formulation of repurposed FDA-approved compounds inhibits Pseudomonas aeruginosa ExoU and improves corneal infection outcomes
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Microbial keratitis caused by Exotoxin U (ExoU)-producing strains of Pseudomonas aeruginosa is associated with poor clinical outcomes and reduced responsiveness to antimicrobial therapy. ExoU, a phospholipase, is secreted directly into host cells, causing thei... ...
