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[Daporinad Potently Induces Cell Death in Ph+ Acute Lymphoblastic Leukemia SUP-B15 Cells Independent of the Intrinsic Apoptotic Pathway]

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Objective: To investigate whether daporinad (APO866), a nicotinamide phosphoribosyltransferase (NAMPT) inhibitor, can potently kill Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) cells via an intrinsic ... ...