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Cooperative definition of ER exit sites by Tango1, Sec16 and Sec12

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Endoplasmic reticulum (ER) exit sites (ERES) are dynamic ER subdomains where secretory cargos are concentrated and exported towards the Golgi apparatus. The conserved proteins Sec16 and Sec12 have long been implicated in ERES organization, while animal-specifi... ...