Effects of propofol on the mRNA transcript abundance of CB1 receptors in rat brain
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This study aimed to elucidate the mechanism underlying tolerance to the sedative effects of propofol, focusing on cannabinoid 1 (CB1) receptor regulation. Male Wistar rats received continuous propofol infusion (30-40 mg/kg/h) for 1, 2, 4, or 12 h prior to tiss... ...
