Lock-Open: An AND Logic-Gated, Entropy-Driven DNA Nanowalker for Highly Sensitive Detection of UDG and APE1 Activities in Hepatocellular Carcinoma
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Early diagnosis of HCC remains a clinical challenge, with survival strongly dependent on reliable biomarkers and translatable detection tools. Herein, we establish uracil-DNA glycosylase (UDG) and apurinic/apyrimidinic endonuclease 1 (APE1) as diagnostic bioma... ...