AID-Mediated Protein Knockdown Reveals the Requirement of NANOS2 in Prenatal Gonocytes for Establishing Functional Spermatogonial Stem Cells
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The RNA-binding protein NANOS2 plays a crucial role in male gonocyte development and the maintenance of spermatogonial stem cells. In the absence of the Nanos2 gene (Nanos2-KO), germ cells fail to enter G0 arrest and initiate the male differentiation program (... ...
