Mechanistic insights into the inhibition of α-synuclein aggregation by sugar-based nanoparticles
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The pathological accumulation of α-synuclein (α-syn) into amyloid fibrils is a key hallmark of Parkinson's disease and related synucleinopathies. Inhibiting the early stages of α-syn aggregation remains a major therapeutic challenge. In this work, we repor... ...