Succinylation of TAGLN2 at K40 drives lipid oxidative stress resistance and TMZ chemoresistance via redox reprogramming in Glioblastoma
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Temozolomide (TMZ) resistance constitutes a primary cause of clinical treatment failure in glioblastoma (GBM). Targeting oxidative cell death to reverse glioma chemoresistance has emerged as a promising novel therapeutic strategy, whereas the core molecular me... ...
