Distinct Reparative and Immunomodulatory Signatures of Extracellular Vesicles From Human Cartilage-Derived Chondroprogenitors, Chondrocytes, and Bone Marrow Mesenchymal Stem Cells in a Rat Osteoarthritis Model
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BackgroundExtracellular vesicles (EVs) mediate many of the reparative effects of cell-based therapies for osteoarthritis; however, the influence of EV source on cartilage repair and systemic immune responses remains unclear. Cartilage-resident chondroprogenito... ...