Cryo-EM structures of apo, agonist- and antagonist-bound heteromeric kainate receptors
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Kainate receptors (KARs) mediate excitatory synaptic transmission and regulate neurotransmitter release. In the central nervous system, KARs predominantly exist as heterotetramers comprising low-affinity (GluK1-3) and high-affinity (GluK4-5) subunits, with Glu... ...
