Structure-based design of peptide inhibitors targeting the SPSB2-iNOS interaction: a computational approach to modulating nitric oxide signaling
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Dysregulation of inducible nitric oxide synthase (iNOS) plays a central role in inflammatory diseases, cancer, and neurodegeneration due to excessive nitric oxide (NO) production. Suppressor of Cytokine Signaling Box Protein 2 (SPSB2) is a key negative regulat... ...
