Sporadic Burkitt Lymphoma Lacking MYC Protein Expression: A Rare Entity With Diagnostic Pitfalls and Dismal Prognosis
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The pathognomonic genetic alteration in Burkitt lymphoma (BL) is the immunoglobulin (IG)-MYC translocation, causing intense nuclear MYC expression in almost all cases. Rare cases harbor MYC rearrangements yet lack detectable MYC protein expression. In this stu... ...