Edaravone Attenuates Carbonyl-Stress-Driven ApoA-I Carboxymethylation and Macrophage Cholesterol-Handling Dysfunction in Diabetic Atherosclerosis
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Diabetes increases atherosclerotic risk significantly, yet the molecular mechanisms linking diabetes-associated carbonyl stress to HDL dysfunction remain insufficiently defined. This study delineated a glyoxal-ApoA-I pathway in diabetes-associated atherosclero... ...