Triplet Radio-Chemo-Immunotherapy Reprograms the PD-L1-CDK6 Axis to Remodel the Tumor Microenvironment and Overcome Immune Resistance in Head and Neck Cancer
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Head and neck squamous cell carcinoma (HNSCC) remains a highly aggressive malignancy with limited therapeutic success and frequent resistance to standard chemoradiotherapy. Beyond its cytotoxic effects, radiotherapy (RT) has emerged as a potent immune modulato... ...