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Pre-existing and Cross-Reactive Immunity to Avian Influenza H5N1 in Humans: Implications for Pandemic Risk and Vaccine Strategies

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Due to the continuous evolution of Influenza A viruses (IAVs), novel strains with efficient human-to-human transmission may emerge and cause future pandemics. Among these, highly pathogenic avian influenza (HPAI) H5N1 remains a major concern because of its imp... ...