Probenecid enhances relaxation induced by cyclic adenosine monophosphate- and cyclic guanosine monophosphate-augmenting substances in rat prostate, bladder, and corpus cavernosum: a potential repurposing strategy
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Prostate, bladder, and corpus cavernosum share common pathophysiological mechanisms involving smooth muscle tone regulation through cyclic nucleotide signaling, particularly cAMP and cGMP pathways. Probenecid, a classical uricosuric agent, has emerged as a can... ...