首页 正文

Notch2 signaling instructs viral and bacterial TLR responsiveness in B cells

{{output}}
Marginal zone (MZ) B cells optimize protection against blood-borne bacteria by rapidly producing plasma cells in response to Toll-like receptor (TLR) ligands. Here, we demonstrate that Notch2 instructs this responsiveness for both the dsRNA sensor TLR3 and LPS... ...