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Aberrant mucin expression and keratinization distinguishing severe from mild asthma revealed by interpretable machine learning

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Type 2 (T2) immune cells dominate the airways of mild-moderate asthma (MMA) patients with a more complex Type 1 (T1)-T2 mixed immune response evident in treatment-refractory severe asthma (SA). We hypothesized that comparing the transcriptomes of the airway ep... ...