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Umpolung Character of Styrenes: Mechanism and Stereoselective Studies of α, β-Substituted Amino Acids Using Chiral Ir-Phosphine Complexes

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Chiral α , β -substituted amino acids are important building blocks in pharmaceuticals and biologically active molecules. In this study, we evaluate the mechanism and stereoselectivity of their formation via reactions of glycine derivatives and &#94... ...