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A rigorous standardized uptake value-based framework for monitoring tafamidis response in transthyretin cardiac amyloidosis with bone-avid single-photon emission computed tomography/computed tomography

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Background: Bone scintigraphy with technetium-labeled tracers has become a cornerstone in diagnosing transthyretin cardiac amyloidosis (ATTR-CM). While visual grading systems like the Perugini Score are widely used, they lack sen... ...