TRIM31 promotes lenvatinib resistance and stemness in hepatocellular carcinoma through K48/K63-linked ubiquitination of GLDC
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Hepatocellular carcinoma (HCC) is a type of cancer with a high incidence rate and a high mortality rate and is a major cause of cancer-related death. The resistance of liver cancer cells to lenvatinib has become a crucial limitation that restricts the clinical... ...