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Gestational NO₂ exposure induces anxiety- and depression-like behaviors in mice via hippocampal PTGDS-PGD2 activation and tryptophan metabolism reprogramming

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Depression is a growing threat to adolescent health worldwide. NO2 potentially contributes to depression onset. A knowledge gap exists in the characterization of neurotoxicity in early life caused by prenatal NO2 exposure. In this study, pregnant C57BL/6 mice ... ...