A new series of FAP inhibitors for cancer imaging based on 8-substituted (4-quinolinoyl)-glycyl-2-cyanopyrrolidine
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Fibroblast activation protein (FAP) is highly expressed in cancer-associated fibroblasts across most epithelial tumors but FAP is nearly absent in normal tissues, making it an attractive target for cancer imaging and therapy. Small-molecule FAP inhibitors have... ...
