Autophagy dysfunction in pancreatic acinar cells in acute pancreatitis: from molecular mechinery and trypsinogen activation to heterogeneity and therapeutic implications
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Acute pancreatitis (AP) is a common acute and critical disease of the digestive system. The initial step of its pathogenesis is the abnormal activation of trypsinogen within pancreatic acinar cells. Seminal studies have identified autophagy dysfunction as a cr... ...
