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Ultrasound-triggered platelet vehicles loading fluorescein for targeted sonodynamic therapy of glioblastoma

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Glioblastoma (GBM), the deadliest primary brain malignancy, resists treatment because of the blood‒brain barrier (BBB) and intrinsic resistance mechanisms. Fluorescein (FL), a clinically approved fluorophore, shows promise as a sonosensitizer for sonodynamic ... ...