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Regulatory role of RamA and RamR in AcrAB-TolC-mediated carbapenem resistance in carbapenem-resistant hypervirulent Klebsiella pneumoniae

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Objective: Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP), which possesses both high pathogenicity and drug resistance, has become a major clinical challenge. The role of AcrAB-TolC efflux pump in its resistan... ...