[Development and application of a method for quantifying plasma cell-free DNA concentration based on Spike-in controls and high-throughput sequencing]
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Plasma cell-free DNA (cfDNA), mainly originates from cellular apoptosis and necrosis, serves as a crucial non-invasive biomarker. Whole-genome bisulfite sequencing (WGBS) allows for the dissection of tissue- and cell-type-specific contributions of cfDNA, enabl... ...
