The bile acid-sensive ion channel (BASIC) is expressed in pancreatic α-cells and involved in glucagon secretion
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Pancreatic α-cells play a key role in glucose homeostasis through glucagon secretion. Here, we discover that the bile acid-sensitive ion channel (BASIC), a Na+ channel of the DEG/ENaC family, has a hitherto unrecognized role in α-cell function. We found that... ...