Tobacco exposure induces T cell exhaustion and dysregulated interactions with epithelial cells in the tumor microenvironment of esophageal squamous cell carcinoma
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Smoking is a well-established risk factor for esophageal squamous cell carcinoma (ESCC), yet its impact on the tumor microenvironment (TME) remains incompletely understood. Using single-cell RNA sequencing of ESCC samples, we identified distinct TME compositio... ...
