High-throughput screening identification of USP7 inhibitors reveals YM155 as a biologically active scaffold with in vivo antitumor efficacy
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Targeting the ubiquitin-proteasome system has emerged as a powerful therapeutic strategy in oncology, particularly through modulation of deubiquitinating enzymes that regulate the stability of oncogenic proteins. Among these, ubiquitin-specific protease 7 (USP... ...
