首页 正文

SARS-CoV-2 ORF7a drives mitochondrial dysfunction via PDK4 activation and complex I inhibition

{{output}}
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection reprograms host metabolism to favor viral replication and immune evasion, yet the contribution of accessory proteins remains poorly defined. Here, we characterize the metabolic effects of t... ...