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Production, purification, and crystallization of the recombinant HER2 tyrosine kinase domain (HER2-TKD)

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The human epidermal growth factor receptor 2 tyrosine kinase domain (HER2-TKD) is an important therapeutic target in oncology. In this study, we developed a practical and cost-effective approach for producing soluble recombinant HER2-TKD in Escherichia coli as... ...