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Perovskite immunoadjuvant: Remodeling the immunosuppressive microenvironment via photothermal catalysis to enhance T-cell recruitment and amplify the immune response

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Immunotherapeutic efficacy is markedly compromised in "cold" tumors, largely as a consequence of the immunosuppressive milieu within the TME, characterized by hypoxia, a fortified antioxidant defense (e.g., elevated glutathione), and insufficient immunogenic... ...