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Transgenic Conversion of Omega-6 to Omega-3 Fatty Acids via fat-1 Reduces Obesity-Related Intervertebral Disc Degeneration

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Introduction: Low back pain is a leading cause of disability, largely due to intervertebral disc (IVD) degeneration. Obesity is a risk factor for IVD degeneration and promotes the release of pro-inflammatory cytokines from adipoc... ...