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Impact of apolipoprotein Ε4 (APOE ε4) on neuroimaging outcomes in cognitively healthy midlife adults: A systematic review

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Background: The apolipoprotein E ε4 (APOE ε4) allele is the strongest genetic risk factor for Alzheimer's disease (AD); however, its neurobiological impact assessed by neuroimaging outcomes during midlife, before the onset of ... ...